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Category Archives: Research & Science

Equine Stamina & Recovery; Influence of Two Key Herbs

Equine performance, stamina, recovery, and overall health are tied in together.  For centuries, various “tonic” herbs have been utilized in Chinese and Ayurvedic medical cultures, to help rebuild and promote vitality in the body, especially post illness or in cases of mental or physical exhaustion. Two key herbs stand out regarding their known ability to ‘revive’ or reenergize the body: Cordyceps sinensis and Astragalus membranaceus. In a search on Pubmed.gov, there are 853 cited papers on Astragalus membranaceus and 1118 on Cordyceps sinensis.  This give us an idea of the vast amount of research conducted and the potential applications towards health restoration. (more…)

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Evaluation of Berry and Citrus Herb Formula in Equine Metabolic Patients

Evaluation of Berry and Citrus Herb Formula in Equine Metabolic Patients

Tom Schell, D.V.M., CVCH

Introduction:

Metabolic syndrome is a term used referring to a group of risk factors that contribute to an increased risk of heart disease, diabetes and stroke in people. In horses, metabolic syndrome is closely connected with poor sugar metabolism, insulin dysfunction, circulatory disease and laminitis.  In both groups, the risk factor that is most prominent is obestity or excessive body condition, which then tends to increase the risk for development of other factors and further contribute to patient health deterioration.  

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Radioprotective Effects of Curcumin & Prostate Cancer

A Pilot Clinical Trial of Radioprotective Effects of Curcumin Supplementation in Patients with Prostate Cancer
 
Abstract (Hejazi, J. et al. J Cancer Sci Ther, Volume 5(10) 320-324 (2013) – 320)
Background: Patients with prostate cancer who accede to radiation therapy usually experience several side effects and these toxicities are sometimes dose limiting. Some previous in vitro and in vivo studies have proposed a radioprotective role for curcumin, the yellow pigment of turmeric.

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Curcumin Bioavailability

Comparative bioavailability of curcumin, turmeri and Biocurcumax (BCM-95®) in traditional vehicles using non-everted rat intestinal sac model

Abstract: (Shishu, Maheshwari, M., Journal of Functional Foods (2010), doi:10.1016/j.jff.2010.01.004)

The bioavailability of curcumin from turmeric, Biocurcumax and as plain curcumin wasinvestigated using conventional vehicles by a non-everted rat intestinal model.

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Curcumin and Rheumatoid Arthritis

A Randomized, Pilot Study to Assess the Efficacy and Safety of Curcumin in Patients with Active Rheumatoid Arthritis Abstract (Chandran B., Goel A., Phytothera. Res 2012) Curcumin is known to possess potent antiinflammatory and antiarthritic properties. This pilot clinical study evaluated the safety and effectiveness of curcumin alone, and in combination with diclofenac sodium in patients with active rheumatoid […]

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Anxiety Reduction and Improved Physical Cooperation in Horses Through the Use of Withania somnifera (Ashwaghanda)

An Observational Clinical Study

by Tom Schell, D.V.M, CVCH, DABVP(eq)

Introduction:

Anxiety and stress in horses are a common problem in the equine industry, contributing to behavioral problems, training issues and poor performance.  In some cases, increased levels of anxiety are associated with health related issues such as gastric ulcers, which have been shown in some studies to impact a large percentage of horses, necessitating long term administration of anti-ulcer type of medications.

 Exact causes of stress in the horse can be hard to determine, but are often linked to herd issues, housing conditions, environmental factors, handling methods, training, transportation and competition.  Horses are very similar to humans in the respect that they respond better to consistency and routines on a day to day basis.  Any upset in that routine can contribute to stress formation which then manifests as behavioral issues.  Learned behaviors or responses to stress in prior environments can transfer forward even though the prior initiating factor has been resolved. 

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Knee Osteoarthritis and Administration of Curcumin & Boswellia

Abstract.: A formulation containing Curcuma longa and Boswellia serrata extracts (CB formulation) was evaluated for safety and efficacy in osteoarthritic patients and directly compared with the selective COX-2 inhibitor, celecoxib. In total, 54 subjects were screened, 30 subjects were enrolled and 28 completed the study. The treatment was well tolerated and did not produce any adverse effect in patients, as judged by the vital signs, hemogram, liver and renal function tests. The CB formulation at 500 mg administered twice a day, was more successful than administering celecoxib 100 mg twice a day for symptom scoring and clinical examination. The formulation was found to be safe and no dose-related toxicity was found.

KIZHAKKEDATH, R., Clinical evaluation of a formula containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis, Mol Med Rep, 8; 1542-48, 2013

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Laminitis in the Horse

What is Laminitis?

Laminitis is inflammation of the laminae, which is the tissue that secures the coffin bone or distal phalanx to the inside of the hoof tissue. Laminitis is often interchangeable with the laymen’s term, “FOUNDER”.

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What is Insulin Resistance?

Insulin resistance is a form of “pre” diabetes and is unfortunately very common in the horse as well as in humans. Insulin resistance or IR is a physiologic condition in which the cells in the body have a decreased response to insulin.

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