{"id":103150,"date":"2022-05-22T15:40:42","date_gmt":"2022-05-22T20:40:42","guid":{"rendered":"https:\/\/08b67ef4d4.nxcli.io\/?p=103150"},"modified":"2022-05-22T15:40:42","modified_gmt":"2022-05-22T20:40:42","slug":"the-obese-horse-gut-health-and-inflammation","status":"publish","type":"post","link":"https:\/\/nouvelleresearch.com\/index.php\/articles\/103150-the-obese-horse-gut-health-and-inflammation","title":{"rendered":"The Obese Horse, Gut Health, and Inflammation"},"content":{"rendered":"

The digestive microbiome and environment are very important contributors to health and soundness in the horse.\u00a0 In fact, one could conclude from research on the human side that the digestive microbiome IS<\/strong> the key to health and soundness.\u00a0 This concept has been explored in equine medicine and it was about 10 years ago that we demonstrated abnormal bacterial growth patterns in metabolic horses, yet, the concept has just not taken hold in the industry as it should.\u00a0 One key group of horses that are impacted by gut health imbalances are the obese or metabolic syndrome patients.<\/strong><\/em>\u00a0 <\/p>\n

The concept of digestive health and the microbiome in the horse is not a new topic, but has been slowly explored compared to the human side of things.\u00a0 About 10 years ago, we performed over 300 fecal cultures on horses<\/a><\/span> that were overweight and impacted by a variety of issues ranging from allergies to metabolic problems.\u00a0 In those studies, it was quite apparent that this overweight group had higher growth levels of lactic acid bacteria compared to leaner and healthier horses.\u00a0 This imbalance is seen in human studies and heavily contributes to systemic inflammation and many problems from diabetes to cancer and cardiovascular disease.<\/p>\n

Recently, I was flipping through a recent copy of the American Journal of Veterinary Research and was pleased to see a research article titled “Fecal extract from obese horses induces an inflammatory response by murine macrophages in vitro<\/em><\/strong>.”\u00a0 This was taken from the May 2022 edition of the AJVR, Page Roth et al.<\/p>\n

The conclusion to this paper is very relevant and states, ” The increased levels of inflammatory markers induced in marine macrophages by the microbiome of obese horses in vitro suggested important differences in the enteric microbial composition of these horses compared to non-obese horses.\u00a0 Overall, this study showed that the microbiome may play a role in mediating an inflammatory response within the digestive tract of obese horses.<\/em><\/strong>”<\/p>\n

What does all of this mean?\u00a0<\/strong> Essentially, in the study they took feces from obese horses and non-obese horses, then diluted them with water, spun them down and then took the fluid and exposed macrophages to it in suspension.\u00a0 Macrophages are one type of cell involved in the immune response and are capable of producing pro-inflammatory chemicals.\u00a0 After exposure to the non-obese horses, the macrophages were essentially unchanged in their activity, however, after exposure to the obese horses’ fluid, the macrophages began to secrete inflammatory proteins.\u00a0 Thus, there is ‘something’ in that fluid that stimulates those cells to become aggressive, irritated, and inflamed.\u00a0 That ‘something’ is either harmful byproducts produced by the imbalanced bacterial microbiome, or it could be inflammatory chemicals being produced by the immune system in the digestive tract, which then ignites other cells when exposed.<\/p>\n

In human research, they note that the altered microbiome not only induces a local immune response, but chemicals produced or not produced by the altered microbiome, are capable of inducing a whole-body or systemic inflammatory response.\u00a0 This is especially noted when there is ‘leaky gut syndrome’ and increased permeability of the gut with leakage of LPS endotoxin.<\/p>\n

This overall concept or connection between gut health and whole body health or status of inflammation is not new and is something I have tried to convey to most of our readers and clients.\u00a0 In fact, it is so important that more times than not in my consults, I put emphasis upon it as the first line thing to address, even in cases of joint pain.<\/p>\n

The overall point here is that the obese horse, which generally speaking is the standard overweight or easy keeper horse, is experiencing digestive microbiome imbalances and those imbalances are what are creating the sore feet, the overweight body condition, the laminitis, the insulin resistance, the allergies, and more than likely the Cushing’s syndrome or elevated ACTH.\u00a0 That imbalance is something that was created and it is not an infection of sorts.\u00a0 It was created by the owner through feeding methods, lifestyle, stress, lack of turnout, improper supplementation, and over-medication.<\/p>\n

The digestive dysbiosis or imbalance is readily apparent just by looking at feces in a photo during my consultations.\u00a0 Sometimes the feces are solid, sometimes they are loose, but most will have a glistening surface of mucous and more times than not, they are brown in color rather than green, and often exude a sweet odor.\u00a0 Once you are able to recognize this in your horse, then the ‘root’ problem is revealed.\u00a0 If you are battling a health condition in your horse, and managing a complicated regimen of all sorts of supplements and probiotics, then in truth, the regimen is not working and could actually be contributing to the issues.\u00a0\u00a0<\/em><\/strong><\/p>\n

The key to managing most of these cases is to STOP doing what you are doing, step back and re-evaluate everything.\u00a0 Then start over with a new perspective.\u00a0 This means higher quality forage, increased turnout, less stress, no grains, minimal to no synthetic based supplements, and increased exercise.\u00a0 This is one of the hardest things to do for most of my clients in consultations, even though it is the most logical.<\/p>\n

It is interesting to see how many metabolic horses just respond to an increased forage quality diet, increased turnout, no grains and only one supplement which targets the digestive health and microbiome.\u00a0 Many horses are able to accomplish this feat with either the Cur-OST EQ Tri-GUT<\/a><\/strong><\/span> or the Cur-OST EQ Tri-Guggul<\/a><\/strong><\/span>.\u00a0 That’s it, nothing more and nothing less.<\/p>\n

If you have an obese, overweight, or easy-keeper horse with health issues, take a step back and re-evaluate what you are doing.\u00a0 You could just be making matters worse rather than better.<\/strong><\/p>\n

 <\/p>\n

Author:\u00a0 Tom Schell, D.V.M, CVCH, CHN<\/p>\n","protected":false},"excerpt":{"rendered":"

The digestive microbiome and environment are very important contributors to health and soundness in the horse.\u00a0 In fact, one could conclude from research on the human side that the digestive microbiome IS the key to health and soundness.\u00a0 This concept has been explored in equine medicine […]<\/p>\n","protected":false},"author":2524,"featured_media":103159,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[12],"tags":[1145,366,281,208,207,210,1135,3519,1309],"class_list":["post-103150","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-equine-articles","tag-cushings","tag-digestion","tag-easy-keeper","tag-equine","tag-horse","tag-inflammation","tag-metabolic","tag-microbiome","tag-obese"],"yoast_head":"\nThe Obese Horse, Gut Health, and Inflammation - 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