{"id":24476,"date":"2020-10-15T13:32:09","date_gmt":"2020-10-15T18:32:09","guid":{"rendered":"https:\/\/be55915bbd.nxcli.net\/?p=24476"},"modified":"2024-05-13T12:46:13","modified_gmt":"2024-05-13T17:46:13","slug":"impacting-insulin-circulation-metabolic-horse","status":"publish","type":"post","link":"https:\/\/nouvelleresearch.com\/index.php\/articles\/24476-impacting-insulin-circulation-metabolic-horse","title":{"rendered":"Impacting Insulin and Circulation in the Metabolic Horse"},"content":{"rendered":"<p>Metabolic syndrome in the horse is on a steady rise over time.\u00a0 In truth, given the high number of cases, diagnosed or not, it could be considered an epidemic.\u00a0 Metabolic related problems in the horse are an &#8216;effect&#8217; more than a &#8217;cause&#8217;, and if you desire to truly resolve or better manage the problem, it is best to seek cause rather than stifle the effects.\u00a0 There are many options in the metabolic horse which can assist you in accomplishing this feat, but now, there are even newer and potentially more effective therapies.\u00a0 Let&#8217;s dive into them!<!--more--><\/p>\n<figure id=\"attachment_24534\" aria-describedby=\"caption-attachment-24534\" style=\"width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-24534 size-medium\" title=\"Gynostemma, Gymnema, Banaba Leaf In Metabolic Horse\" src=\"https:\/\/nouvelleresearch.com\/wp-content\/uploads\/Gynostemma-300x199.jpeg\" alt=\"Gynostemma, Gymnema, Banaba Leaf In Metabolic Horse\" width=\"300\" height=\"199\" srcset=\"https:\/\/nouvelleresearch.com\/wp-content\/uploads\/Gynostemma-scaled-300x199.jpeg 300w, https:\/\/nouvelleresearch.com\/wp-content\/uploads\/Gynostemma-1024x678.jpeg 1024w, https:\/\/nouvelleresearch.com\/wp-content\/uploads\/Gynostemma-150x99.jpeg 150w, https:\/\/nouvelleresearch.com\/wp-content\/uploads\/Gynostemma-768x509.jpeg 768w, https:\/\/nouvelleresearch.com\/wp-content\/uploads\/Gynostemma-1536x1017.jpeg 1536w, https:\/\/nouvelleresearch.com\/wp-content\/uploads\/Gynostemma-2048x1356.jpeg 2048w, https:\/\/nouvelleresearch.com\/wp-content\/uploads\/Gynostemma-scaled-400x265.jpeg 400w, https:\/\/nouvelleresearch.com\/wp-content\/uploads\/Gynostemma-scaled.jpeg 1300w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-24534\" class=\"wp-caption-text\">Gynostemma, Gymnema, Banaba Leaf In Metabolic Horse<\/figcaption><\/figure>\n<p>EMS or equine metabolic syndrome is a complex cascade of events in the horse creating a multitude of health and soundness problems.\u00a0 In taking a rough guess based on experience, as to how many horses are impacted, I would estimate upwards of 65-70%.\u00a0 This estimation includes not only the obvious cases of metabolic syndrome in the horse, being overweight and sore footed, but includes a large percentage of equine athletes who go undiagnosed despite clinical problems.<\/p>\n<p>Metabolic syndrome is a complex cascade of events, as mentioned above.\u00a0 For some horses, the main issue is being overweight, while in others there are foot related problems including laminitis or just sole tenderness.\u00a0 In some, the metabolic related cellular events cause problems regarding tendon and ligament health, performance and recovery.\u00a0 The bottom line in all of them is that there is a disruption of normal cellular metabolism.\u00a0 Does this have to result in an overweight horse? Not in all cases, but one thing is for certain and that is that an overweight horse has an increased tendency towards metabolic concerns.<\/p>\n<p>There are many therapy options for managing the average metabolic horse, which have been discussed in numerous articles.\u00a0 The bottom line goal in helping the average EMS horse is to improve cellular function and health.\u00a0 This can be accomplished through many methods, some more potent or effective than others.\u00a0 The precise approach required for each individual horse can vary dependent on the severity of their condition and other factors such as diet, medications being given, and exercise.\u00a0 There are many working &#8216;arms&#8217; in the creation of metabolic syndrome in the horse, thus, there is never &#8216;ONE&#8217; thing that will resolve the problem.\u00a0 More so, it is a matter of altering many factors along with the proper use of nutrition and herbal therapy that will provide the best results in the majority of cases.<\/p>\n<p>The vast majority of metabolic horses are plagued with insulin dysfunction and glucose metabolism problems, which are then connected to and secondarily create other inflammatory events such as foot pain, laminitis, and circulatory problems.\u00a0 These are all tied together.<\/p>\n<p>In this article, our goal is to introduce you to some new formulas which have provided immense benefit in some of our small clinical trials in equine patients.\u00a0 These options are now readily available, but do require some knowledge and know-how, in their use and choosing between them.<\/p>\n<h3><span style=\"color: #3366ff;\">Gynostemma, Gymnema, and Banaba Leaf in the Metabolic Horse<\/span><\/h3>\n<p>There are many herbs which can impact insulin function and glucose regulation in the horse, but many accomplish this feat secondarily.\u00a0 This means that the herbs are used and known for other main clinical benefits, but as an effect, they do modulate insulin and glucose metabolism.\u00a0 This is not their primary function essentially, but a secondary effect.\u00a0 Curcumin is one of them, as an example.<\/p>\n<p><em>Gynostemma<\/em> (Jiaogulan), <em>Gymnema<\/em>, and <em>Lagerstroemia<\/em> (Banaba leaf) are three herbs that are well known and heavily researched for their ability to impact insulin function and glucose or sugar metabolism.\u00a0 One of them, <em>Gynostemma<\/em> (Jiaogulan) is also utilized by many horse owners already in various doses to help them to manage their metabolic patients.\u00a0 Despite its usage, <em>Gynostemma<\/em> does not always yield favorable results in every horse, which is true for almost every herb.\u00a0 This is where and why we get into herb energetics, proper dosing, and synergism with other herbs.<\/p>\n<p><em>Gynostemma<\/em> is an herb used in Traditional Chinese Medicine to assist diabetic patients with glucose metabolism and weight loss.\u00a0 <em>Gymnema<\/em> is an herb used in Ayurvedic medicine to assist their diabetic patients with glucose metabolism and weight loss.\u00a0 Banaba leaf is an herb utilized in the Philippines for the exact same purposes.\u00a0 Three different medical cultures, same end goals, but different herbs. All three herbs are also heavily researched in the medical fields with documented papers noting clinical benefits when it comes to sugar metabolism, insulin function, and in some cases, weight reduction. Their usage goes back decades if not centuries in alternative medical fields.<\/p>\n<p>All herbs used for medicinal purposes have within them phytochemicals which exert the health benefits, whether that be antioxidant properties, glucose lowering abilities, cardiovascular benefits, or curbing inflammatory events.\u00a0 It is these phytochemicals that we are interested in as they are responsible for most of the clinical benefits.\u00a0 <em>Gynostemma pentaphyllum<\/em> possesses many phytochemicals but the main ones of research interest are called Gypenosides.\u00a0 <em>Gymnema sylvestre<\/em> also possesses many phytochemicals with Gymnemic acids being of research interest, that not only can impact glucose metabolism and blood sugar levels, but interestingly &#8216;numbs&#8217; the tongue to the point where the sweet taste of sugar is blunted.\u00a0 Banaba is much the same but the main chemical of interest is called Corosolic acid.\u00a0 These individual phytochemicals are the area of interest in research and are what appear to be responsible for most of the &#8216;metabolic&#8217; type of benefits to the herbs.\u00a0 Of course, there are other phytochemicals present, but it is important to concentrate as much as possible on the primary phytochemicals as it allows for dose reduction and likely an improved efficacy in benefiting the metabolic horse.<\/p>\n<p>When it comes to herbs, there are many herbs that can accomplish a certain task or provide health benefits, but every herb is not ideal for every patient, including the horse.\u00a0 Every herb has within it an energy and effects.\u00a0 Some herbs are warming, some cooling, and some outright heating to the body.\u00a0 Others can be moisturizing, while some are drying.\u00a0 Some are sweet and benefit digestion, while others can create upset in an already ulcerated environment.\u00a0 All three of these herbs; <em>Gynostemma<\/em>, <em>Gymnema<\/em>, and Banaba Leaf are cooling in nature and mildly drying upon the body.\u00a0 This is a good thing for most metabolic horses given that the vast majority of them do not do well in the heat and humidity of the spring and summer, and most of them have retained moisture or <span style=\"color: #ff6600;\"><strong><a style=\"color: #ff6600;\" href=\"https:\/\/nouvelleresearch.com\/index.php\/articles\/18437-ama-dampness-equine-digestive-health\">dampness<\/a><\/strong><\/span> within their bodies.<\/p>\n<p>Going further, it is interesting to note that most metabolic horses, like their human counterparts, have disrupted digestive microbiomes which equates to digestive problems, dampness in the body, weight retention, and inflammatory events.\u00a0 These three herbs; <em>Gynostemma<\/em>, <em>Gymnema<\/em>, and Banaba Leaf, due to their energetic properties are also highly beneficial to the digestive tract and microbiome, so there are additional benefits.\u00a0 Going one step further, all three herbs have been demonstrated to modify and balance the inflammatory events in the body.\u00a0 Thus, there is a win-win in most metabolic horses with clinical problems.<\/p>\n<p><strong>The ideal scenario when using herbs is to use them in combination to achieve synergism<\/strong>.\u00a0 This is how herbs are used in Ayurvedic and Traditional Chinese Medicine for optimal results.\u00a0 Combinations allow for reduced doses and the ability to take advantage of synergism, which is built on similar benefits between herbs.\u00a0 For many horse owners, herbs are used individually and often haphazardly with little direction or intent.\u00a0 This can create problems and further imbalances if you are not careful, hurting rather than helping.<\/p>\n<p>In our ongoing research in the metabolic horse, we have found synergism between <em>Gynostemma<\/em>, <em>Gymnema,<\/em> and Banaba leaf, using their concentrated extracts for optimal benefits and a lower dose. In our clinical trials, horses on the herbal blend as a stand alone with no other herbs given, demonstrated a reduced pre and post-prandial glucose, reduced fasting glucose, and a higher post-prandial ketone level.\u00a0 This translates into the fact that the majority of horses on this blend demonstrated much improved glucose control with lower levels and a higher ketone level after eating, which would equate to improved insulin function.\u00a0 Additionally, the horses on the herbal blend appeared more content, less irritable, more comfortable in hot environments and had reduced foot pain.\u00a0 These clinical benefits are the result of the improved glucose metabolism, insulin function, and likely reduced inflammation and improved digestive microbiome.<\/p>\n<p>The herbal formula that we were using in those clinical trials is the <span style=\"color: #ff0000;\"><strong><a style=\"color: #ff0000;\" href=\"https:\/\/nouvelleresearch.com\/index.php\/product\/cur-ost-eq-i-s\">Cur-OST EQ I.S<\/a><\/strong><\/span>., which is a synergistic blend of the three herbs in their concentrated extracts.\u00a0 This blend worked well for upwards of 80% of the horses with improvement noted in as little as 14 days with no side effects.\u00a0 Some digestive upset was noted at increased doses, however, which is likely due to the cooling nature of the herbs.<\/p>\n<h3><span style=\"color: #3366ff;\">Impacting Circulation and Foot Pain in the Metabolic Horse<\/span><\/h3>\n<p>Metabolic syndrome, laminitis and foot pain go hand in hand.\u00a0 Where there is one, there is often the other, although some are not diagnosed or recognized.\u00a0 \u00a0Many metabolic horses have diagnosed laminitis, which is inflammation of the connective tissue surrounding the coffin bone, resulting in foot pain, abnormal hoof growth and perceived rotation of the coffin bone on radiograph.\u00a0 Other horses, however, struggle with plain foot pain which is often the result of an unhealthy and thin sole, necessitating shoes, many times with pads, and an inability to walk on hard or rough surfaces.<\/p>\n<p>The key to resolving these foot situations is to recognize that they are not separate from the main internal problem of metabolic related issues in the horse.\u00a0 If you treat the foot separately, as it&#8217;s own entity, without addressing the internal problems in your horse, you will lose the battle nine out of ten times.\u00a0 This is why many horse owners are constantly dealing with laminitis from one season to the next, or others are constantly switching shoes or using boots to keep their horses comfortable.<\/p>\n<p>In the metabolic horse, foot related pain is associated with circulatory issues created secondary to the insulin dysfunction and lack of proper glucose control.\u00a0 These create inflammatory events in the body which lead to endothelial dysfunction, a fancy term to describe cellular damage inside blood vessels, which can lead to improper blood flow.<\/p>\n<p>The primary goal in managing a metabolic horse with foot related pain would be to better manage the insulin dysfunction, inflammation, and secondary circulatory events.\u00a0 Sounds simple, right?\u00a0 It can be for some, but certainly more complex for others.\u00a0 <strong>One again, there is and never will be any &#8216;ONE&#8217; solution which resolve all clinical problems in your horse.<\/strong>\u00a0 Metabolic syndrome and associated events are a result of many factors and for optimal results, all factors are managed.<\/p>\n<p>When it comes to foot pain in the metabolic horse, it is interesting to note that some have more foot discomfort in the warmer times of the year, while others suffer more in the colder seasons.\u00a0 This is not unusual in any way, but signifies that there are different patterns present.\u00a0 On a basic level, the horse that has more problems in the warmer times of the year has more internal &#8216;heat&#8217; inside their body, which is exacerbated by the heat and humidity of the season.\u00a0 The horse which has more problems during the colder times of the year has more &#8216;cold&#8217; present in their body, which is likewise made worse by the colder environmental temperatures.\u00a0 The &#8216;hotter&#8217; metabolic horse seems to be improved during the cooler seasons while the &#8216;colder&#8217; metabolic horse stabilizes during the warmer times.<\/p>\n<p><em><strong>What&#8217;s the importance of this observation?<\/strong><\/em>\u00a0 You need to determine which one is your horse and use herbs appropriately to benefit their condition.<\/p>\n<p>When it comes to improving circulation and blood flow, there are many herbs that impact circulation and blood flow throughout the body of the horse.\u00a0 Traditionally, herbs like Turmeric and Boswellia are heavily relied upon, with Turmeric being more warming and Boswellia more cooling in nature.\u00a0 Additionally, there is Hawthorn Leaf and Berry\u00a0 as well as Dan Shen or <em>Salvia miltiorrhiza<\/em>, both of which are well researched for their benefit to the cardiovasculat system and circulation.\u00a0 Hawthorn leaf and berry\u00a0 is also used in Traditional Chinese Medicine to benefit digestion.<\/p>\n<p>All of these herbs contain phytochemicals which demonstrate clinical health benefits.\u00a0 Hawthorn leaf and berry are both known for the chemical called vitexin, Turmeric for the phytochemical called curcumin, and many others as well..\u00a0 There are numerous benefits to these phytochemicals including improved blood circulation, altered nitric oxide levels, and balanced inflammation.\u00a0 The metabolic horse can benefit from all of these.<\/p>\n<p>Ideally, we combine these circulatory herbs with the main three herbs to impact insulin function and glucose metabolism, especially in the metabolic horse with foot related pain.\u00a0 In our clinical studies, both circulatory herbs in conjunction with <em>Gymnema<\/em>, <em>Gynostemma<\/em>, and Banaba Leaf extracts resulted in improved foot comfort in about 14 days with a reduced digital pulse.\u00a0 These results have been far superior to anything we have witnessed to date, considering they were a stand alone blend, and only the diet was modified otherwise.<\/p>\n<p><strong>There are several Cur-OST and Secondvet herbal formulas that can benefit circulation in the horse, including:<\/strong><\/p>\n<ol>\n<li><span style=\"color: #ff0000;\"><strong><a style=\"color: #ff0000;\" href=\"https:\/\/nouvelleresearch.com\/index.php\/product\/cur-ost-eq-pure\">Cur-OST EQ Pure<\/a><\/strong><\/span> &#8211; warming formula to enhance circulation<\/li>\n<li><span style=\"color: #ff0000;\"><strong><a style=\"color: #ff0000;\" href=\"https:\/\/nouvelleresearch.com\/index.php\/product\/cur-ost-eq-pure\">Cur-OST EQ Inflammend<\/a> <\/strong><\/span>&#8211; warming formula to enhance circulation<\/li>\n<li><span style=\"color: #ff0000;\"><strong><a style=\"color: #ff0000;\" href=\"https:\/\/secondvet.com\/product\/eq-foot-body-sore-pain\/\">Secondvet EQ Foot &amp; Body<\/a> <\/strong><\/span>&#8211; neutral formula to benefit circulation<\/li>\n<\/ol>\n<p>There are many approaches to benefit the metabolic horse and improve their quality of life.\u00a0 These herbal formulas are just one of many, but offer much promise and benefit, even when used alone with dietary modifications and lifestyle adjustments.<\/p>\n<p><strong>For more information on managing the metabolic horse, check out our book:<\/strong><\/p>\n<p><span style=\"color: #ff0000;\"><strong><a style=\"color: #ff0000;\" href=\"https:\/\/nouvelleresearch.com\/index.php\/product\/metabolic-horse-repairing-the-mechanism\">The Metabolic Horse; Repairing the Mechanism<\/a><\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p>Author:\u00a0 Tom Schell, D.V.M, CVCH, CHN<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Metabolic syndrome in the horse is on a steady rise over time.\u00a0 In truth, given the high number of cases, diagnosed or not, it could be considered an epidemic.\u00a0 Metabolic related problems in the horse are an &#8216;effect&#8217; more than a &#8217;cause&#8217;, and if you desire [&hellip;]<\/p>\n","protected":false},"author":2524,"featured_media":24534,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[12],"tags":[5645,5644,3362,208,742,1176,5643,5642,5648,5647,720,207,210,879,280,233,279,1177,5646,5641],"class_list":["post-24476","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-equine-articles","tag-arjuna","tag-banaba-leaf","tag-circulation","tag-equine","tag-foot-pain","tag-glucose","tag-gymnema","tag-gynostemma","tag-hawthorn-berry","tag-hawthorn-leaf","tag-herbs","tag-horse","tag-inflammation","tag-insulin","tag-insulin-resistance","tag-laminitis","tag-metabolic-syndrome","tag-sugar","tag-terminalia-arjuna","tag-thin-soles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Impacting Insulin and Circulation in the Metabolic Horse 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