{"id":318,"date":"2014-02-02T21:11:43","date_gmt":"2014-02-02T21:11:43","guid":{"rendered":"https:\/\/nouvelleresearch.j96fp4es-liquidwebsites.com\/2014\/02\/02\/curcumin-and-rheumatoid-arthritis\/"},"modified":"2021-07-25T12:36:09","modified_gmt":"2021-07-25T17:36:09","slug":"curcumin-and-rheumatoid-arthritis","status":"publish","type":"post","link":"https:\/\/nouvelleresearch.com\/index.php\/articles\/318-curcumin-and-rheumatoid-arthritis","title":{"rendered":"Curcumin and Rheumatoid Arthritis"},"content":{"rendered":"<div>\n<p><strong><span style=\"font-size: 12pt;\">A Randomized, Pilot Study to Assess the Efficacy&nbsp;and Safety of Curcumin in Patients with Active&nbsp;Rheumatoid Arthritis<\/span><\/strong><\/p>\n<p><span style=\"font-size: 10pt;\">Abstract (Chandran B., Goel A., Phytothera. Res 2012)<\/span><\/p>\n<div>Curcumin is known to possess potent antiinflammatory and antiarthritic properties. This pilot clinical study evaluated&nbsp;the safety and effectiveness of curcumin alone, and in combination with diclofenac sodium in patients with&nbsp;active rheumatoid arthritis (RA). Forty-five patients diagnosed with RAwere randomized into three groups with&nbsp;patients receiving curcumin (500 mg) and diclofenac sodium (50 mg) alone or their combination. The primary&nbsp;endpoints were reduction in Disease Activity Score (DAS) 28. The secondary endpoints included American&nbsp;College of Rheumatology (ACR) criteria for reduction in tenderness and swelling of joint scores. Patients in&nbsp;all three treatment groups showed statistically significant changes in their DAS scores. Interestingly, the curcumin&nbsp;group showed the highest percentage of improvement in overall DAS and ACR scores (ACR 20, 50 and 70)&nbsp;and these scores were significantly better than the patients in the diclofenac sodium group. More importantly,&nbsp;curcumin treatment was found to be safe and did not relate with any adverse events. Our study provides the&nbsp;first evidence for the safety and superiority of curcumin treatment in patients with active RA, and highlights&nbsp;the need for future large-scale trials to validate these findings in patients with RA and other arthritic conditions.<\/div>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>A Randomized, Pilot Study to Assess the Efficacy&nbsp;and Safety of Curcumin in Patients with Active&nbsp;Rheumatoid Arthritis Abstract (Chandran B., Goel A., Phytothera. Res 2012) Curcumin is known to possess potent antiinflammatory and antiarthritic properties. This pilot clinical study evaluated&nbsp;the safety and effectiveness of curcumin alone, and [&hellip;]<\/p>\n","protected":false},"author":2524,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"enabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":null,"stick-header-meta":null,"header-above-stick-meta":null,"header-main-stick-meta":null,"header-below-stick-meta":null,"astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[135],"tags":[203,210,238,312,761,759,760],"class_list":["post-318","post","type-post","status-publish","format-standard","hentry","category-research-science","tag-curcumin","tag-inflammation","tag-joint-pain","tag-pain","tag-pain-relief","tag-ra","tag-rheumatoid-arthritis"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - 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