Metabolic syndrome is a name applied to a collective group of risk factors that raise the risk of other health conditions. In humans, we see a rise in the risk of heart disease, stroke, diabetes, vascular disorders, neurodegenerative conditions and many others. In horses, we generally see an increased risk for insulin resistance, Cushing’s disease and laminitis. The term ‘metabolic’ actually implies an alteration in cellular metabolism or biochemical processes, but is often quickly associated with a state of increased body weight or obesity. The syndrome is actually complex, involving many pathways, but as with other conditions, with a more indepth understanding comes better management.