Research & Science Articles
Published: JAHVMA, volume 29, no. 1, 2010, p 11-15 Oxidative Stress, Implications in Equine Orthopedic Disease, Insulin Resistance, and a Potential Target for […]
Read MoreOxidative Stress in a Small Population of TB Racehorses Tom Schell, D.V.M., DABVP, CVCH Introduction: Oxidative stress is part of the inflammatory […]
Read MoreThe equine digestive microbiome has become an area of interest in recent research, attempting to determine if connections exist with other health and lameness concerns. […]
Read MoreSpirulina Health Benefits
Spirulina in Health Care Management
Kulshreshtha, A., Current Pharmaceutical Biotechnology, 2008, Vol. 9, No. 5
Read MoreRadioprotective Effects of Curcumin & Prostate Cancer
Curcumin Bioavailability
Comparative bioavailability of curcumin, turmeri and Biocurcumax (BCM-95®) in traditional vehicles using non-everted rat intestinal sac model
Abstract: (Shishu, Maheshwari, M., Journal of Functional Foods (2010), doi:10.1016/j.jff.2010.01.004)
The bioavailability of curcumin from turmeric, Biocurcumax and as plain curcumin wasinvestigated using conventional vehicles by a non-everted rat intestinal model.
Read MoreCurcumin and Rheumatoid Arthritis
A Randomized, Pilot Study to Assess the Efficacy and Safety of Curcumin in Patients with Active Rheumatoid Arthritis Abstract (Chandran B., Goel A., Phytothera. Res 2012) Curcumin […]
Read MoreAnxiety Reduction and Improved Physical Cooperation in Horses Through the Use of Withania somnifera (Ashwagandha)
An Observational Clinical Study
by Tom Schell, D.V.M, CVCH, DABVP(eq)
Introduction:
Anxiety and stress in horses are a common problem in the equine industry, contributing to behavioral problems, training issues and poor performance. In some cases, increased levels of anxiety are associated with health related issues such as gastric ulcers, which have been shown in some studies to impact a large percentage of horses, necessitating long term administration of anti-ulcer type of medications.
Exact causes of stress in the horse can be hard to determine, but are often linked to herd issues, housing conditions, environmental factors, handling methods, training, transportation and competition. Horses are very similar to humans in the respect that they respond better to consistency and routines on a day to day basis. Any upset in that routine can contribute to stress formation which then manifests as behavioral issues. Learned behaviors or responses to stress in prior environments can transfer forward even though the prior initiating factor has been resolved.
Read MoreKnee Osteoarthritis and Administration of Curcumin & Boswellia
Abstract.: A formulation containing Curcuma longa and Boswellia serrata extracts (CB formulation) was evaluated for safety and efficacy in osteoarthritic patients and directly compared with the selective COX-2 inhibitor, celecoxib. In total, 54 subjects were screened, 30 subjects were enrolled and 28 completed the study. The treatment was well tolerated and did not produce any adverse effect in patients, as judged by the vital signs, hemogram, liver and renal function tests. The CB formulation at 500 mg administered twice a day, was more successful than administering celecoxib 100 mg twice a day for symptom scoring and clinical examination. The formulation was found to be safe and no dose-related toxicity was found.
KIZHAKKEDATH, R., Clinical evaluation of a formula containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis, Mol Med Rep, 8; 1542-48, 2013
Read MoreCurcumin & Equine Osteoarthritis
Equine osteoarthritis is a debilitating, degenerative condition affecting horses of various age groups and with a multitude of causes, ranging from conformational flaws, trauma to infectious origins.
Read MoreAn Observational Study of a Proprietary Herbal Formula in Controlling the Clinical Signs of COPD and Allergies in Equine Patients
Tom Schell, D.V.M, DABVP, CVCH
Skin allergies and Chronic Obstructive Pulmonary Disease are two common clinical problems affecting horses, especially in the eastern and southern portions of the United States.
Read MoreCurcumin Research & Science
Curcumin and Inflammation Abstract – Pro-inflammatory cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor-alpha (TNF-α) play a key role in the pathogenesis of osteoarthritis (OA). Once released, these cytokines are potent stimulators
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